
Striving for a safe and flourishing world
An independent think tank with a mission to transform global resilience to extreme risks
Our Vision
Our vision is a safe and flourishing world with high resilience to extreme risks, such as those from pandemics and emerging technologies.
Our Mission
Our mission is to transform global resilience to extreme risks — both in the UK and internationally. Our core focus areas are AI risk, biological risk and government risk management
We help governments and other institutions transform resilience to extreme risks by:
Our Latest Work
Artificial Intelligence
Risks stemming from improper application, unintended behaviours of AI systems in critical domains, and the broader socioeconomic impacts of AI on both the economy and society.
Why frontier AI safety frameworks need to include risk governance
This report outlines why risk governance should be enhanced in future versions of safety frameworks, along with recommendations for AI companies and Governments
Transforming risk governance at frontier AI companies
This report explores how aspects of best practice risk governance – particularly the Three Lines Model (3LoD), which separates risk ownership, oversight and
Biosecurity
Risks arising from natural pandemics, laboratory leaks, bioweapons, and ‘dual-use’ research — advancements with the potential for both beneficial and harmful applications.
Biological Tools and the EU AI Act
In this report, we examine the definitions of general-purpose and systemic risk as classified in the EU AI Act and discuss how these
CLTR’s Response to the National Institute of Standards and Technology’s Safety Considerations for Chemical and/or Biological AI Models
The Centre for Long-Term Resilience recently contributed to the National Institute of Standards and Technology’s Safety Considerations for Chemical and/or biological AI models.
Risk Management
Global-reaching, high-impact threats possess the potential to cause widespread devastation to both lives and economies on a global scale.
The Government’s response to the Covid Inquiry and the National Risk Register 2025: Our thoughts
On January 16, 2025 the Government published its response to Module 1 of the Covid-19 Inquiry, outlining its stance on the Inquiry’s 10
Transforming risk governance at frontier AI companies
This report explores how aspects of best practice risk governance – particularly the Three Lines Model (3LoD), which separates risk ownership, oversight and