Shape of a globe
Shape of a globe
Shape of a globe

Striving for a safe and flourishing world

An independent think tank with a mission to transform global resilience to extreme risks

Our Vision

Our vision is a safe and flourishing world with high resilience to extreme risks, such as those from pandemics and emerging technologies.

Our Mission

Our mission is to transform global resilience to extreme risks — both in the UK and internationally. Our core focus areas are AI risk, biological risk and government risk management

We help governments and other institutions transform resilience to extreme risks by:

Helping decision-makers and the wider public to understand extreme risks.
Providing expert advice and red-teaming on policy decisions.
Convening cross-sector conversations and workshops related to extreme risks.
Developing and advocating for policy recommendations and effective risk management frameworks and systems.
Providing an exchange for specialist knowledge, including by facilitating expert placements into government.

Our Latest Work

Artificial Intelligence

Risks stemming from improper application, unintended behaviours of AI systems in critical domains, and the broader socioeconomic impacts of AI on both the economy and society.

Priorities for the UK Government on frontier AI risk and Biosecurity


Sep 9, 2026

AI loss of control incidents are worsening, shows CLTR analysis


Aug 29, 2026

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Biosecurity

Risks arising from natural pandemics, laboratory leaks, bioweapons, and ‘dual-use’ research — advancements with the potential for both beneficial and harmful applications.

Priorities for the UK Government on frontier AI risk and Biosecurity


Sep 9, 2026

Progress on Biosecurity in the European Biotech Act


CLTR responds to the amendments tabled by the joint SANT and ITRE committees and to the ENVI and JURI opinions. We set out

Aug 12, 2026

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Risk Management

Global-reaching, high-impact threats possess the potential to cause widespread devastation to both lives and economies on a global scale.

Ten things we want to see from Exercise Pegasus


What does best-in-class risk preparedness exercising look like? We outline ten key benchmarks we’ll be watching for from Exercise Pegasus to demonstrate the

Feb 12, 2026

UK Resilience Action Plan: Ambitious Progress with Room to Go Further


Jul 25, 2025