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Topic/Area:

Biosecurity

Safeguarding against pandemics and addressing extreme biological risks through targeted policy engagement

Introduction

We work to enhance global preparedness against extreme biological risks. By engaging government, policymakers, academics and industry, we advise on strategies to bolster pandemic prevention, strengthen biosecurity measures, and promote the responsible development of biotechnologies. 

We believe that responsible innovation can lead to a prospering bioeconomy that delivers transformative benefits while mitigating biosecurity risks.

CLTR biosecurity policy meeting sat around conference table
AI Biosecurity policy fringe event - panel on stage

Our current focus

  • Developing a new risk index to monitor AI-enabled biological tools in collaboration with RAND Europe
  • Investigating the benefits of a thriving UK bioeconomy for reduction in biological risks
  • Examining the resilience of the UK domestic manufacturing supply chain in biological events
  • Supporting the effective implementation of the UK’s 2023 Biological Security Strategy
  • Advising government and frontier AI labs on the risks at the intersection of artificial intelligence and biology, including through forum such as the General-Purpose AI Code of Practice, Frontier AI Safety Framework Conference and direct engagement

Featured Work

Biosecurity

Progress on Biosecurity in the European Biotech Act


CLTR responds to the amendments tabled by the joint SANT and ITRE committees and to the ENVI and JURI opinions. We set out

Aug 12, 2026

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Gap consolidation of the mirror life evidence base


This blog post and accompanying spreadsheet identify specific, safe knowledge gaps to fill for preparedness without lowering the barriers to creating mirror life.

Jan 16, 2026

Cost-Benefit Analysis of Synthetic Nucleic Acid Screening for the UK


Through a cost-benefit analysis, we found that mandatory screening synthetic nucleic acids over 50 base pairs in length bought or sold in the

Dec 16, 2025

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Defensive acceleration: the strategic pivot needed for UK biological resilience


A framework and four priority programmes to grow the economy and strengthen UK biosecurity in the age of AI.

Jan 30, 2026

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What we want to see

  • Adequate funding and resources are allocated to fully implement the UK’s 2023 Biological Security Strategy plan and achieve its fifteen outcome commitments by 2030
  • The development and operationalisation of the National Biosurveillance Network as a critical tool for early detection and response to novel pathogen outbreaks
  • Uptake of UK screening guidance on synthetic nucleic acids to prevent access to dangerous biological materials
  • A thriving UK bioeconomy with resilient domestic supply chains that delivers prosperity and reduces biological risk
  • Expansion of the US-UK Strategic Dialogue on Biological Security beyond 2024, driving collaborative efforts to enhance global resilience against the full spectrum of biological threats

£376 million

UK government public spending on COVID-19

51

Biosafety Level 4 (BSL-4) laboratories globally

£1.4 million

Annual budget for the Biological Weapon Convention Implementation Support Unit

Our future plans

Assist the UK in becoming the global leader in responsible innovation of engineered biology, capitalising on the potential while mitigating the risks

Ensure robust risk assessment is conducted at the intersection of artificial intelligence and biosecurity

Ensure full implementation of the UK’s Biological Security Strategy