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Biosecurity

Progress on Biosecurity in the European Biotech Act

Dr Michael Mahar


CLTR responds to the amendments tabled by the joint SANT and ITRE committees and to the ENVI and JURI opinions. We set out

Aug 12, 2026

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Biosecurity

Informing the European Biotech Act and Inclusions of our Recommendations

Dr Cassidy Nelson


In November 2025, the Biosecurity Policy Unit submitted written evidence to the European Union (EU)’s Public Consultation informing the European Biotech Act.

Feb 6, 2026

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Biosecurity

Defensive acceleration: the strategic pivot needed for UK biological resilience

Dr Richard Moulange, Oliver Payne, Dr Paul-Enguerrand Fady & Dr Cassidy Nelson


A framework and four priority programmes to grow the economy and strengthen UK biosecurity in the age of AI.

Jan 30, 2026

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Laboratory worker holding two petri dishes showing bacterial colonies
Biosecurity

Gap consolidation of the mirror life evidence base

Dr Paul-Enguerrand Fady, Dr Sarah Winthrope, Dr James Walker and Dr Cassidy Nelson


This blog post and accompanying spreadsheet identify specific, safe knowledge gaps to fill for preparedness without lowering the barriers to creating mirror life.

Jan 16, 2026

Biosecurity

Cost-Benefit Analysis of Synthetic Nucleic Acid Screening for the UK

Dr Paul-Enguerrand Fady, Isaac Heron, Dr Richard Bruns and Dr Cassidy Nelson


Through a cost-benefit analysis, we found that mandatory screening synthetic nucleic acids over 50 base pairs in length bought or sold in the

Dec 16, 2025

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Biosecurity

Simulations suggest that antibiotics would not work on mirror bacterial targets

Dr Paul-Enguerrand Fady and Dr JL Ciccone


Our results suggest that, of the existing antibiotic countermeasures we tested, none were effective against their mirror targets. This implies that these antibiotics

Nov 28, 2025

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Biosecurity

Two Years On: An Independent Assessment of the UK’s Biological Security Strategy Implementation

Oliver Payne and Dr Cassidy Nelson


In light of the UK Cabinet Office's two-year update on the BSS Implementation Report, CLTR is providing a narrative response that highlights critical

Oct 27, 2025

Biosecurity

Public Services Committee Call for Evidence: Medicines Security

Dr Paul-Enguerrand Fady


To bolster UK supply chains and increase self-sufficiency of MCM manufacturing, CLTR recommends specific measures be considered by the UK Government.

Oct 10, 2025

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Biosecurity

Strengthening UK Science Leadership: Our Parliamentary Submission on Science Diplomacy

Dr Paul-Enguerrand Fady


In this submission of evidence, we draw on extensive experience in biosecurity, innovation policy, and international collaboration to identify structural barriers preventing the

Sep 18, 2025

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Biosecurity

Strategic Defence Review 2024: Call for Evidence

Oliver Payne


We submitted detailed recommendations to the Ministry of Defence's Strategic Defence Review 2024, focused on Chemical, Biological, Radiological, and Nuclear (CBRN) threats expected

Sep 10, 2025

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Biosecurity

Securing Europe’s Biotechnology Future: Our European Biotech Act Submission

Dr Cassidy Nelson


We submitted recommendations to the European Commission's consultation on the European Biotech Act, emphasising that security and innovation are complementary objectives.

Sep 10, 2025

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Biosecurity

Strengthening EU Medical Countermeasures: Our Strategic Recommendations

Dr Paul-Enguerrand Fady


We submitted recommendations to DG HERA's call for evidence on the EU strategy for medical countermeasures against public health threats, drawing on our

Sep 10, 2025

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Biosecurity

Global Risk Index for AI-enabled Biological Tools

Toby Webster, Richard Moulange, Barbara Del Castello, James Walker, Sana Zakaria and Cassidy Nelson


The CLTR-RAND team introduce the first Global Risk Index for AI-enabled Biological Tools: a flexible framework designed to assess these tools based on

Sep 9, 2025

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Biosecurity

The Strategic Defence Review: A Biosecurity Perspective

Oliver Payne, Cassidy Nelson, Richard Moulange, James Ginns, and Tommy Shaffer Shane


Jun 6, 2025

Biosecurity

Biosecurity must not become a casualty of the trade war

Paul-Enguerrand Fady and Oliver Payne


Rising geoeconomic tensions put cross-border cooperation at risk.

Apr 9, 2025

Biosecurity

Recent poll suggests that the UK public expects the Government to prepare for future pandemics and address rising biological risks

Frankie Di-Nozzi


To better understand public attitudes towards biological threats, The Centre for Long-Term Resilience, in partnership with Public First, recently conducted a nationwide poll

Mar 14, 2025

Biosecurity

Boosting UK supply chain resilience to mitigate catastrophic biological risks

Paul-Enguerrand Fady, Frankie Di-Nozzi, Oliver Payne and Cassidy Nelson


The best time to bolster UK supply chain resilience for medical countermeasures was yesterday. The second best time is now.

Mar 14, 2025

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Biosecurity

Growing the UK Bioeconomy

Oliver Payne, Paul-Enguerrand Fady, Frankie Di-Nozzi, Sarah Winthrope and Cassidy Nelson


In this report, we propose 6 recommendations that will help grow the UK bioeconomy and build national resilience against future biological events.

Feb 24, 2025

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Biosecurity

Biological Tools and the EU AI Act

Richard Moulange, Tina Wünn and Cassidy Nelson


In this report, we examine the definitions of general-purpose and systemic risk as classified in the EU AI Act and discuss how these

Jan 8, 2025

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Biosecurity

CLTR’s Response to the National Institute of Standards and Technology’s Safety Considerations for Chemical and/or Biological AI Models

Richard Moulange and Cassidy Nelson


The Centre for Long-Term Resilience recently contributed to the National Institute of Standards and Technology's Safety Considerations for Chemical and/or biological AI models.

Dec 27, 2024

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