Publications

Biological Tools and the EU AI Act
Richard Moulange, Tina Wünn and Cassidy Nelson
In this report, we examine the definitions of general-purpose and systemic risk as classified in the EU AI Act and discuss how these

CLTR’s Response to the National Institute of Standards and Technology’s Safety Considerations for Chemical and/or Biological AI Models
Richard Moulange and Cassidy Nelson
The Centre for Long-Term Resilience recently contributed to the National Institute of Standards and Technology's Safety Considerations for Chemical and/or biological AI models.

CLTR’s response to the UK Government’s Industrial Strategy consultation (Invest 2035)
Paul-Enguerrand Fady
The Centre for Long-Term Resilience recently contributed to the Industrial Strategy open consultation led by the Department for Business and Trade (DBT).

UK Screening Guidance: Collated list of biological agents and toxins
Paul-Enguerrand Fady, Lucy Di-Nozzi and The Centre for Long-Term Resilience Biosecurity Policy Unit
To help support the uptake of the UK screening guidance, The Centre for Long-Term Resilience has collated a list of biological agents and

Independent Progress Tracker: UK Biological Security Strategy
In June 2023, the UK Cabinet Office published an updated national Biological Security Strategy (BSS) outlining the government’s plan to strengthen the UK’s

Capability-Based Risk Assessment for AI-Enabled Biological Tools
Richard Moulange, Sophie Rose*, James Smith, Cassidy Nelson†
Life sciences research and industries are undergoing a rapid transformation due to advancements in artificial intelligence (AI).

The near-term impact of AI on biological misuse
Sophie Rose*, Richard Moulange, James Smith, Cassidy Nelson†
Various broad claims have been made about the impact of AI on biological misuse risk. Some argue that AI is likely to provide

How the UK Government should address the misuse risk from AI-enabled biological tools
James Smith, Sophie Rose, Richard Moulange, Cassidy Nelson
Advances in AI-enabled biological tools (BTs) are catalysing life sciences research.

Why we recommend risk assessments over evaluations for AI-enabled biological tools (BTs)
James Smith, Sophie Rose, Richard Moulange, Cassidy Nelson
As part of our work to identify the three most beneficial next steps that the UK Government can take to reduce the biological

Overcoming challenges with synthetic nucleic acid screening implementation
Cassidy Nelson and Sophie Rose
In October 2023, The Centre for Long-Term Resilience’s Biosecurity Policy Unit brought together stakeholders across academia, policy and the private sector to run

Understanding AI-Facilitated Biological Weapon Development
Cassidy Nelson and Sophie Rose
Artificial intelligence and biotechnology are converging in a way that could catalyse immense progress from areas like personalised medicine to sustainable agriculture—as well

Building the UK’s Resilience to Future Pandemic Threats
A submission of evidence to the UK Government’s public inquiry into the UK’s preparations for, and response to, the COVID-19 pandemic

Biosecurity Policy Proposals
Sophie Rose
Transform UK and global resilience to the full range of biological threats.

Policy Proposals
CLTR's policy experts have set out a series of proposals to transform the UK's resilience to extreme risks. Our recommendations focus on areas

Extreme Risks and The UK National Resilience Strategy
James Ginns
A new joint paper by Dr Toby Ord at Oxford's Future of Humanity Institute, Dr Seán Ó hÉigeartaigh at Cambridge's Centre for the

Introducing Future Proof: a roadmap to boost the UK’s resilience to extreme risks
Sophie Dannreuther
We’re proud to launch Future Proof, in collaboration with Toby Ord, author of The Precipice, and extreme risk experts from the Future of